Hidradenitis Suppurativa

Hidradenitis Suppurativa (HS)

Hidradenitis suppurativa, is a chronic inflammatory skin condition with lesions, deep-seated nodules and abscesses, draining tracts, and fibrotic scars. These lesions most commonly occur in intertriginous areas and areas rich in apocrine glands. Among the most common are the axillary, groin, perianal, perineal, and inframammary locations.

Treatment varies based on severity, but due to pain, sensitive locations, drainage, odor, and scarring, this condition also has a negative psychosocial impact.¹

https://www.ncbi.nlm.nih.gov/books/NBK534867/

HS Dataset Overview

Clinically Deep | Amplifying Hurley Stage

OM1’s augmentation of our rich foundational data through automated and manual note abstractions reveals Hurley Stage.
Machine Learning-generated estimated Hurley Stage (eHurley) across the dataset will amplify the number of patients classified.

Hurley Stage classifications in the OM1 HS dataset

| Use Case

Identify biologic-eligible patients, Hurley Stage 2 or 3, in HS patients

Challenge

Understanding the specific patient characteristics that show which HS patients are likely to respond to biologic therapy.

Solution

Leverage OM1 linked, clinical EMR and claims data that includes Hurley stage, steroid dosing and exposure. OM1 data also includes extracted disease activity descriptors for body location and use of bDMARDs.